Amoxicillin is sometimes preferred over penicillin in children because of its taste.Ĭommon Adverse Drug Reactions: Amoxicillin is well-tolerated, but some common complaints can be gastrointestinal (GI) symptoms, such as nausea, vomiting, and diarrhea. Patients should not crush Extended-release tablets, and the administration should be within 1 hour after finishing a meal.
The administration should take place immediately after mixing. It may be mixed (after thoroughly shaking) and administered with formula, milk, water, fruit juice, ginger ale, or other cold drinks if given in suspension. It also comes in a chewable tablet or a suspension. Amoxicillin comes in immediate-release or extended-release tablets.
Īmoxicillin is an oral antimicrobial whereas, ampicillin (which is structurally similar) can be given orally, intravenously, or intramuscularly. The more “around-the-clock” dosing provides minor variation in peak and trough serum concentrations. Therefore, they are often dosed more frequently, rather than the concentration-dependent drugs, which can be dosed, for example, daily. Time-dependent refers to the time that serum concentrations exceed the minimum-inhibitor-concentration (MIC) for the microorganism. Bactericidal antimicrobials, such as amoxicillin, often are most effective in a “time-dependent” manner rather than a “concentration-dependent” manner.
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